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UMP biosynthesis I

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
electron-transfer_quinone + L-dihydroorotate <=> electron-transfer_quinol + Orotate 1.3.5.2 dihydroorotate dehydrogenase (quinone)

orotidine_5''-phosphate + diphosphate <=> 5-phospho-alpha-D-ribose_1-diphosphate + Orotate 2.4.2.10 orotate phosphoribosyltransferase

L-dihydroorotate + H2O <=> H+ + L-carbamoyl-L-aspartate 3.5.2.3 dihydroorotase

ATP + L-glutamine + HCO3- + H2O <=> L-glutamate + Carbamoyl_phosphate + ADP + phosphate + H+ 6.3.4.16 carbamoyl-phosphate synthase (ammonia)
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)


L-aspartate + Carbamoyl_phosphate <=> H+ + L-carbamoyl-L-aspartate + phosphate 2.1.3.2 aspartate carbamoyltransferase

H+ + orotidine_5''-phosphate <=> CO2 + UMP 4.1.1.23 orotidine-5'-phosphate decarboxylase

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